Fred Fack Selected Research

isocitric acid (isocitrate)

12/2017	Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.
5/2013	Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

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Fred Fack Research Topics

Disease

10	Neoplasms (Cancer) 01/2021 - 03/2011
5	Glioma (Gliomas) 01/2021 - 09/2010
5	Glioblastoma (Glioblastoma Multiforme) 12/2015 - 03/2011
2	Measles 11/2010 - 01/2003
1	Astrocytoma (Pilocytic Astrocytoma) 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2014
1	Prostatic Neoplasms (Prostate Cancer) 06/2012
1	Carcinogenesis 06/2012
1	Vascular Remodeling 03/2011
1	Hypoxia (Hypoxemia) 03/2011
1	Infections 07/2004

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 02/2016 - 09/2010
3	EnzymesIBA 01/2021 - 01/2015
3	NADP (NADPH)IBA 01/2021 - 05/2013
3	Glutathione (Reduced Glutathione)IBA 01/2021 - 01/2015
3	Pharmaceutical PreparationsIBA 01/2021 - 09/2010
2	AntioxidantsIBA 01/2021 - 06/2012
2	CystathionineIBA 01/2021 - 12/2017
2	isocitric acid (isocitrate)IBA 12/2017 - 05/2013
2	Oxidoreductases (Dehydrogenase)IBA 12/2017 - 05/2013
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2015 - 03/2011
2	Bevacizumab (Avastin)FDA Link 01/2015 - 03/2011
1	propargylglycineIBA 01/2021
1	Cysteine (L-Cysteine)FDA Link 01/2021
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021
1	LyasesIBA 01/2021
1	ChromatinIBA 12/2017
1	CarbonIBA 12/2017
1	Glucose (Dextrose)FDA LinkGeneric 12/2017
1	Phospholipids (Phosphatides)FDA LinkGeneric 12/2017
1	DNA (Deoxyribonucleic Acid)IBA 12/2017
1	Biological ProductsIBA 02/2016
1	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 12/2015
1	NucleotidesIBA 12/2015
1	Tricarboxylic AcidsIBA 12/2015
1	Glutamic Acid (Glutamate)FDA Link 12/2015
1	Glutamine (L-Glutamine)FDA Link 12/2015
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2015
1	Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA 01/2015
1	epidermal growth factor receptor VIIIIBA 09/2013
1	ErbB Receptors (EGF Receptor)IBA 09/2013
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2013
1	alpha-hydroxyglutarateIBA 05/2013
1	AndrogensIBA 06/2012
1	CurcuminIBA 06/2012
1	Alanine (L-Alanine)FDA Link 03/2011
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2011
1	Protein Isoforms (Isoforms)IBA 11/2010
1	ProteomeIBA 09/2010
1	Biomarkers (Surrogate Marker)IBA 09/2010
1	Explosive Agents (Explosives)IBA 07/2004
1	AntigensIBA 01/2003
1	VaccinesIBA 01/2003

Therapy/Procedure

1	Therapeutics 01/2015